In stage 4 breast cancer, immunotherapy is often combined with chemotherapy. In stage 1 to 3 triple-negative breast cancer, immunotherapy can be used to shrink a tumor before surgery. The only approved immunotherapy for triple-negative breast cancer is pembrolizumab. Like chemotherapy, immunotherapy can also help to shrink tumors before surgery. Immunotherapy is a treatment that helps the immune system identify and kill cancer cells. This helps select the best chemotherapy treatment for after surgery.Ĭhemotherapy medications for triple-negative breast cancer include doxorubicin, carboplatin, paclitaxel, docetaxel, and cyclophosphamide. This helps to better understand how well the cancer responds to the chemotherapy. Stages 2 to 3: Chemotherapy is often used before surgery. Stage 1: It’s more common to give chemotherapy after surgery. But chemotherapy is used to prevent the cancer coming back.Ĭhemotherapy can be given before or after surgery, depending on the stage of triple-negative breast cancer: Surgery is the main treatment for triple-negative breast cancer. The surgeon usually performs a lymph node biopsy at the same time. This can be a mastectomy (removal of the whole breast) or a lumpectomy (removal of the tumor). If the cancer is in stages 1 to 3, the primary treatment is surgery. Options include surgery, chemotherapy, immunotherapy, and radiation therapy. ![]() The treatment for triple-negative breast cancer depends on the stage. If none of these receptors are present, the cancer is called “triple negative.” How do you treat triple-negative breast cancer? These tests include checking for the estrogen, progesterone, and HER2 receptors. When a biopsy shows cancer, more tests are done on the tissue. A provider will take a sample of the tissue and look at it under the microscope. If the imaging suggests breast cancer, the next step is a biopsy. Imaging tests may include more mammograms, ultrasounds, or MRI scans. When a person has an abnormal mammogram or a lump in the breast, the next step is usually more imaging. How do you diagnose triple-negative breast cancer? For example, cancer that has spread to the bones often causes pain. When breast cancer has spread to other parts of the body, the symptoms depend on where the cancer is located. In other cases, a person may feel a lump in the breast or in the lymph nodes under the arm. In these cases, the person often doesn’t have any symptoms. In other words, triple-negative breast cancers generally have the same symptoms as other breast cancers.īreast cancer is often found on a screening mammogram. The symptoms of different breast cancers are the same. What are the symptoms of triple-negative breast cancer? Since triple-negative breast cancers don't have these receptors, these medications don’t work.įor these reasons, triple-negative breast cancer is harder to cure than other breast cancers. Similarly, trastuzumab works on the HER2 receptor. For example, medications like tamoxifen work on the estrogen receptor. ![]() ![]() Many breast cancer treatments don’t work in triple-negative breast cancer. Triple-negative breast cancer is also more likely than other breast cancers to metastasize (spread) to other parts of the body. This means they look very different from normal breast cells. They grow quickly, and the cells are usually high grade. Triple-negative breast cancers tend to be aggressive. View more medications How is triple-negative breast cancer different from other types of breast cancer?
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